Chrono-aging is the progressive weakening in the skin renewal process over time, leading to the worsening of the dermis, hypodermis and support structures. This results in the deterioration and destruction of the skin’s main components (collagen, elastin) and the impairment of skin as the moisture-retaining barrier, leading to increased Trans Epidermal Water Loss (TEWL) and the decrease of skin hydration level (GAG). The adverse effect of this type of aging becomes noticeable around the age of 30. If not properly treated, this eventually leads to ECM breakdown, resulting in wrinkles and dull skin. To reverse this relentless aging process, strong counter-measures are required. Chrono-aging is often referred also as “Intrinsic aging” and is mainly genetics-determined.
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